Accelerating Cloud-based Genomics Pipelines Through I/O Profiling for Analysis of More Than 3,000 Whole Genome Pairs on AWS

This paper presents an overview of the work by the Wellcome Sanger Institute to make one of their cancer pipelines portable and to tune it for cloud deployment using the Altair Breeze™ and Altair Mistral™ I/O profiling tools. With the insight from the tools we were able to tune the cloud configuration to boost speed by 20% with a cost reduction of 10%.