Oftentimes, in the design of a casting, suboptimal structural concepts are developed which at the same time are not castable, requiring multiple and time-consuming design iterations. This paper describes a process to generate both structurally efficient and also castable parts, while reducing the overall design cycle time. The optimal structure is determined by topology optimization, reducing component mass while maintaining performance requirements. This step is followed by a design smoothing operation and then by a casting simulation to check for casting defects. To demonstrate this software driven product design and process validation, solidThinking Inspire® is used to develop the concept design and Click2Cast® for casting process validation.